Scientists have developed a method to rejuvenate old and damaged human cells by replacing their mitochondria. With new mitochondria, the previously damaged cells regained energy production and function. The rejuvenated cells showed restored energy levels and resisted cell death.

https://engineering.tamu.edu/news/2025/11/recharging-the-powerhouse-of-the-cell.html

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  1. Researchers at Texas A&M University **have developed a method to rejuvenate old and damaged human cells by replacing their mitochondria.**

    Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production — a finding that could have revolutionary effects across medicine.

    Mitochondrial decline is linked to aging, heart disease and neurodegenerative disorders. Enhancing the body’s natural ability to replace worn-out mitochondria could fight all of them.

    As human cells age or are injured by degenerative disorders like Alzheimer’s or exposure to damaging substances like chemotherapy drugs, they begin to lose their ability to produce energy. The culprit is a decrease in the number of mitochondria — small, organ-like structures within cells responsible for producing most of the energy cells use. From brain cells to muscle cells, as the number of mitochondria drops, so does the health of the cells, until they can no longer carry out their functions.

    The study, published in Proceedings of the National Academy of Sciences, used a combination of microscopic flower-shaped particles — called nanoflowers — and stem cells. In the presence of these nanoflowers, the stem cells produced twice the normal amount of mitochondria. When these boosted stem cells were placed near damaged or aging cells, they transferred their surplus mitochondria to their injured neighbors.

    **With new mitochondria, the previously damaged cells regained energy production and function. The rejuvenated cells showed restored energy levels and resisted cell death**, even after exposure to damaging agents such as chemotherapy drugs.

    For those interested, here’s the link to the peer reviewed journal article:

    https://www.pnas.org/doi/10.1073/pnas.2505237122

  2. Minimum_Holiday_5611 on

    So when can we see this in action? call me a sceptic. these things are always 10 years in the future

  3. >Scientists have developed a method to rejuvenate old and damaged human cells by replacing their mitochondria. With new mitochondria, the previously damaged cells regained energy production and function. The rejuvenated cells showed restored energy levels and

    #

    >resisted cell death

    Isn’t that cancer?