I am working on a medical AI that can answer not only simple health-related questions, but also diagnose complex clinical cases based on patient symptoms and risk factors. It identifies the most likely patient condition, recommends appropriate diagnostic tests to confirm the diagnosis, and suggests optimal treatment plans.
Initially, I plan to promote the system as a co-pilot for medical students, and later as a second-opinion support tool for clinicians. While some refinement remains, the project is approximately 95% complete. The model rarely hallucinates, thanks to a native medical knowledge graph and a RAG-based answer auditing mechanism.
The core knowledge graph consists of 5,000 medical concept nodes and 25,000 multidirectional edges representing their relationships. I created special tokens derived from graph node and edge IDs and annotated PubMed and MTS medical texts (via text embeddings) with these tokens to help the model better understand medical concepts and their interdependencies.
The underlying model is BioBERT-Large (encoder-only), fine-tuned using LoRA parameters and graph-node-aware text embeddings. As a result, the system is capable of answering medical questions with a high degree of consistency and reasoning fidelity.
You can test the model here:
https://huggingface.co/spaces/cmtopbas/medical-slm-testing
This is a public Hugging Face Spaces demo and does not require any access tokens. You may either use the preset medical questions or submit your own.
I am NOT seeking funding at this stage. Instead, I am looking for co-founders or collaborators with expertise in AI, medical research, or clinical practice, as well as medical institutions (such as medical schools or hospitals) interested in free evaluation and testing with their students or clinicians.
Below are 20 medical questions with model-generated answers. All were run in a single batch, with no cherry-picking.
✓ Graph loaded: 4,388 nodes
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QUESTION 1/19
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Q: 60 Year-old Male patient reports persistent chest pain radiating to the left arm.
He has from of hypertension and Type 2 diabetes.
His Lab ECG test shows ST-segment elevation.
Identify the disease, list risk factors, symptoms, recommended treatment, and contraindications.
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Prompt → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 6
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 15
✓ Graph-validated (Valid)
The diagnosis is acute coronary syndrome with atrial fibrillation . Risk factors are smoking (current), dyslipidemia, family history of cardiovascular diseases, and age over 6 0years. Symptoms are chest pain, shortness of breath, and nausea. Recommended treatment includes aspirin , clopidogrel , statins , and beta blockers . Discontinue anticoagulation therapy if indicated. Contraindications are renal failure and chronic obstructive pulmonary disease . The patient will be followed up at regular intervals for further evaluation and management. Coronary artery bypass grafting should be considered in patients who have had a myocardial infarction within the past year. Age over 6 0years is an independent predictor of mortality after CABG surgery.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 2/19
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Q: A 45-year-old male patient reports frequent urination, excessive thirst and fatigue.
He has a family history of type 2 diabetes and is overweight.
Blood tests show elevated fasting glucose and HbA1c levels.
Identify the disease, list risk factors, symptoms, recommended treatment, and contraindications.
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Prompt → Categories: ['DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 5
Answer → Categories: ['DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 23
✓ Graph-validated (Valid)
The diagnosis is Type 2Diabetes Mellitus (T2DM). Risk factors are obesity, sedentary lifestyle, high blood pressure, dyslipidemia, smoking, and genetic predisposition. Symptoms include increased urinary frequency, nocturia, urgency, and Nocturnal enuresis . Treatment includes diet control with low glycemic index foods, exercise, weight loss, oral hypoglycemic agents, insulin therapy, and surgery if necessary. Risks for complications include hypoglycemia, cardiovascular events, nephropathy, retinopathy, neuropathy, and amputation. Patients should be counseled on these risks as well as potential side effects from medications. There are no known contraindications to any medication used in treating T2DM. Recommendations for follow up include monitoring glycated hemoglobin level every three months, checking urine protein dipstick test at least once per month, measuring serum creatinine concentration yearly, performing an electrocardiogram annually, and obtaining a complete medical history including past surgical procedures. Diabetic Ketoacidosis (DKA) can occur when patients have poorly controlled T2DM. It may present acutely with severe metabolic derangements such as ketoacidosis, but it also occurs chronically without warning signs. Common acute manifestations include vomiting, abdominal pain, nausea, diarrhea, fever, and altered mental status. Chronic features include polyuria, polydipsia, dehydration, and renal failure. Diagnosis requires confirmation by laboratory.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 3/19
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Q: A 30-year-old female patient reports persistent cough, fever, and shortness of breath.
She recently returned from a trip abroad and has a mild history of asthma. Chest X-ray shows patchy infiltrates in the lower lobes.
Identify the disease, list risk factors, symptoms, recommended treatment, and contraindications.
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Prompt → Categories: ['DiagnosticTest', 'Disease', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 5
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 10
✓ Graph-validated (Valid)
The diagnosis is Mycobacterium tuberculosis (TB). Risk factors are smoking, alcohol abuse, immunosuppression, and recent travel to an endemic area. Symptoms include productive cough with mucopurulent sputum, night sweats, and weight loss. Treatment includes four months of isoniazid, rifampin, pyrazinamide, and ethambutol followed by two years of isoniazid and rifampicin. There are no known contraindications for this regimen. This infection can be treated successfully if diagnosed early enough before it progresses into active disease. Pulmonary alveolar proteinosis (PAP) should also be considered as a differential diagnosis when patients present with similar clinical features. PAP results from impaired surfactant clearance due to decreased activity of GM-CSF receptor on macrophages leading to accumulation of lipoproteinaceous material within alveoli. Patients typically have progressive dyspnea, dry cough, and hypoxemia requiring oxygen supplementation. Diagnosis requires lung biopsy which demonstrates characteristic findings including foamy cells containing PAS positive granules. PAP may occur sporadically but more commonly presents as part of a syndrome called autoimmune PAP caused by autoantibodies against GM-CSFR. Corticosteroids and immunosuppressive agents such as rituximab are used to treat both forms of PAP; however, there is currently no cure for either form of PAP. Lung transplantation is another option that must be discussed with the patient.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 4/19
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Q: A 50-year-old male patient experiences abdominal pain, bloating, and intermittent diarrhea.
He has a family history of celiac disease and reports gluten sensitivity.
Blood tests show elevated anti-tTG antibodies.
Identify the disease, list risk factors, symptoms, recommended treatment, and contraindications.
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Prompt → Categories: ['DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 7
Answer → Categories: ['CellularStructure', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 9
✓ Graph-validated (Valid)
Celiac disease is an autoimmune disorder that affects genetically susceptible individuals with exposure to dietary antigens from wheat (gliadin), rye, barley, oats, and other foods containing these proteins. Symptoms may be nonspecific but can present as malabsorption syndrome, weight loss, anemia, osteoporosis, dermatitis herpetiformis, and Joint swelling . Diagnosis requires serologic testing for immunoglobulin G (IgG) -class autoantibodies against tissue transglutaminase (tTG) in conjunction with small bowel biopsy findings. Treatment includes strict adherence to a lifelong gluten free diet along with regular monitoring by a gastroenterologist. The prognosis depends on early diagnosis and prompt initiation of therapy. Patients should undergo periodic follow up visits at least every 6 months during which they are educated about their condition and its management. Vitamin D deficiency is common among patients with celiac disease due to decreased intestinal absorption secondary to mucosal damage caused by chronic inflammation. It is important to screen all patients with celiac disease for vitamin D deficiency because it increases the risk of bone fractures. Screening guidelines recommend measuring serum 2 5 hydroxyvitamin D levels prior to starting a gluten free diet and after 1 year of treatment if there was no improvement in vitamin D status. If vitamin D insufficiency persists despite adequate supplementation, then further evaluation including measurement of parathyroid hormone level is indicated. In addition, calcium intake must also be monitored closely since low calcium stores increase the risk of developing osteomalacia.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 5/19
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Q: What are the major complications of diabetes?
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Prompt → Categories: ['Symptom'] | Nodes: 0
Answer → Categories: ['BodyPart', 'Disease', 'Symptom', 'Treatment'] | Nodes: 11
✓ Graph-validated (Valid)
Diabetes is a chronic disease that can lead to serious health problems including heart attack and stroke. Complications such as nephropathy, retinopathy, neuropathy, and Diabetic foot ulcer contribute significantly to morbidity in patients with diabetes. The most common complication of diabetes is diabetic nephropathy which affects up to25% of people living with type 1 diabetes mellitus. Other important complications include retinopathy (affecting approximately 2 0-3 0. 0%), peripheral vascular disease (affecting about 5. 5%), and neuropathic pain (occurring in 4. 3% of patients). Recommendations for prevention and treatment were also provided based on current evidence from clinical trials and guidelines. Type I diabetes mellitus is characterized by insulin deficiency resulting from autoimmune destruction of pancreatic beta cells. Patients may develop microvascular complications such as retinopathy, nephropathy, and neuropathy; macrovascular complications such as coronary artery disease and cerebrovascular accident; and other less frequent manifestations such as Hypoglycaemia , Ketoacidosis , and Pulmonary embolism . These complications result in significant disability and increased mortality rates among individuals with type 1 diabetes. Prevention strategies should be implemented early in life.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 6/19
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Q: What diseases could cause chest pain and shortness of breath during exercise?
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Prompt → Categories: ['Disease', 'Symptom'] | Nodes: 3
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'Treatment'] | Nodes: 13
✓ Graph-validated (Valid)
The most likely diagnosis is pulmonary embolism , which can be confirmed by a diagnostic test such as computed tomography (CT) scan. Other possible diagnoses include coronary artery disease , aortic valve stenosis , mitral regurgitation , atrial fibrillation , hypertrophic cardiomyopathy , dilated cardiomyopathy , myocarditis , pericarditis , acute myocardial infarction , pneumonia , chronic obstructive lung disease , asthma , congestive heart failure , sarcoidosis ,.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 7/19
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Q: How does metformin work to treat type 2 diabetes?
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Prompt → Categories: ['Disease', 'Treatment'] | Nodes: 2
Answer → Categories: ['DiagnosticTest', 'RiskFactor', 'Symptom', 'Treatment'] | Nodes: 4
✓ Graph-validated (Valid)
Metformin is a biguanide that has been used for the treatment of type 2Diabetes since 1 9 5 0s and it remains one of the most commonly prescribed medications in this country. It works by decreasing blood glucose levels through several mechanisms including increasing insulin sensitivity, reducing hepatic gluconeogenesis, stimulating peripheral uptake of glucose, inhibiting intestinal absorption of carbohydrates, and promoting glycosuria. The side effects are gastrointestinal upset (nausea, vomiting), lactic acidosis, hypoglycemia, weight gain, and rare cases of hepatotoxicity.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 8/19
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Q: What are symptoms of appendicitis?
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Prompt → Categories: ['Symptom'] | Nodes: 0
Answer → Categories: ['DiagnosticTest', 'Disease', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 4
✓ Graph-validated (Valid)
Symptoms of acute appendicitis can be nonspecific and may mimic other conditions such as gastroenteritis, urinary tract infection, nephrolithiasis, diverticulitis, cholecystitis, cholangitis, pancreatitis, and irritable bowel syndrome . Patients with these conditions often present to the emergency department (ED) for evaluation and treatment; however, they have similar clinical manifestations that overlap considerably. Therefore, it is important to consider a diagnosis of acute appendicitis in patients presenting with symptoms consistent with those described above. The diagnostic approach includes history taking, physical examination, laboratory testing, imaging studies, and surgical consultation when indicated. 2. 2. 2 > acute appendicitis . It also discusses current controversies surrounding this condition including its incidence, risk factors, role of antibiotics, and optimal timing of surgery. Finally, we provide recommendations on how to manage suspected cases of acute appendicitis based on recent evidence from large multicenter trials. Acute appendicitis should always be considered in any patient who presents with.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 9/19
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Q: What is best suited treatment for depressed, lonely, elderly men?
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Prompt → Categories: ['Treatment'] | Nodes: 0
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Symptom', 'Treatment'] | Nodes: 16
✓ Graph-validated (Valid)
Treatment of depression in the elderly should be based on a thorough history and physical examination to determine whether there are any underlying medical conditions that may contribute to the symptoms. The first-line treatments recommended by the American Psychiatric Association (APA) for this condition include selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), electroconvulsive therapy (ECT), and psychotherapy. However, these medications have not been shown to improve outcomes when used as monotherapy; therefore, they must be combined with other therapies such as cognitive behavioral therapy (CBT), interpersonal psychotherapy (IPT), and / or exercise programs. Depression in the Elderly can occur due to many different causes including stress, anxiety, sleep disorders, stroke, dementia, cancer, heart disease, Parkinson's Disease, and drug use. In addition, patients who suffer from depression often present with multiple comorbidities making it difficult to identify which specific cause is responsible for their depressive symptoms. A comprehensive evaluation includes an assessment of psychosocial factors such as social support, family functioning, and life events. If no clear etiology exists, then treatment options include pharmacotherapy, psychotherapy, and / or exercise. When possible, medication should be started at low doses and gradually increased over several weeks until clinical improvement occurs. Patients taking TCAs should also receive concurrent antidepressant prophylaxis with lithium or lamotrigine if they have bipolar disorder. Other drugs commonly prescribed for treating depression include SSRIs, bupropion, mirtazapine, ne.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 10/19
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Q: What are early warning signs of stroke?
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Prompt → Categories: ['Disease'] | Nodes: 1
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'Symptom', 'Treatment'] | Nodes: 11
✓ Graph-validated (Valid)
Early warning signs of stroke can be identified through a thorough history and physical examination. These symptoms should trigger an urgent evaluation by the emergency department (ED) physician to determine if there is any evidence of acute ischemic stroke. The most common presenting symptom in patients with acute ischemic stroke is sudden onset of severe headache. Other common early warning signs include nausea, vomiting, dizziness, weakness, numbness, speech disturbance, confusion, and loss of consciousness.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 11/19
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Q: Causes and treatment of blood during urination?
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Prompt → Categories: ['Treatment'] | Nodes: 0
Answer → Categories: ['DiagnosticTest', 'Disease', 'Symptom', 'Treatment'] | Nodes: 9
✓ Graph-validated (Valid)
Blood is a common finding in patients with urinary tract infections (UTIs). It can be caused by an infection itself, but it may also occur as part of the normal physiological response to UTI symptoms such as fever, chills, nausea, vomiting, diarrhea, and abdominal pain. The cause should be determined through history taking and physical examination. Treatment options for blood during urination are limited; however, if there is no evidence of sepsis, antibiotics should not be administered unless indicated based on clinical signs and symptoms.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 12/19
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Q: What is treatment for lack of sexual drive in middle aged women after menopause?
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Prompt → Categories: ['Treatment'] | Nodes: 0
Answer → Categories: ['RiskFactor', 'Riskfactor', 'Treatment'] | Nodes: 4
✓ Graph-validated (Valid)
Treatment for lack of sexual desire in middle-aged women includes hormone replacement therapy (HRT) and psychotherapy. HRT should be considered as first line treatment due to its low risk profile compared with other treatments such as antidepressants and psychotherapy.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 13/19
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Q: Causes of rapid excessive weight gain?
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Prompt → Categories: [] | Nodes: 0
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Treatment'] | Nodes: 16
✓ Graph-validated (No prompt entities)
The causes of rapid excessive weight gain are varied and can be classified as either genetic (e. g. , Prader-Willi syndrome ) or environmental (e. g. , Polycystic ovary syndrome ). Genetic causes should be considered in patients with a history of rapid weight gain before the age of 20years who have an abnormal body mass index at presentation. Environmental causes may present later during life but must also be evaluated if there is no known cause for rapid weight gain. Patients presenting with rapid weight gain require thorough evaluation to determine its etiology. A detailed medical history and physical examination will help guide further diagnostic testing. Laboratory tests including complete blood count, liver function test, thyroid stimulating hormone level, fasting glucose levels, lipid panel, insulin resistance markers such as C reactive protein and leptin, and serum prolactin levels should be obtained. Imaging studies such as magnetic resonance imaging of the brain and pituitary gland, abdominal ultrasound, bone scan, electrocardiogram, echocardiogram, pulmonary artery pressure measurement by echocardiography, and renal ultrasonography should be performed when indicated based on clinical findings. Treatment options vary depending on the underlying cause; however, lifestyle modifications remain the mainstay of therapy. Weight loss medications such as orlistat and liraglutide have been shown to improve obesity outcomes. Surgical interventions such as gastric banding and sleeve gastrectomy have proven effective in achieving sustained weight reduction over time.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 14/19
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Q: How is pneumonia diagnosed and treated?
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Prompt → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'Treatment'] | Nodes: 2
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Riskfactor', 'Symptom', 'Treatment'] | Nodes: 10
✓ Graph-validated (Valid)
Pneumonia can be diagnosed based on clinical signs and symptoms including fever, cough, shortness of breath, chest pain, and oxygen saturation (SpO2) Community-Acquired Pneumonia : Diagnostic Criteria, Treatment Options, and Prognosis in Adults. Community-Acquired Pneumonia is characterized by respiratory distress due to bacterial invasion into lung tissue. It affects people of all ages but has highest incidence rates among older individuals. Risk factors include advanced age, underlying medical conditions, cigarette smoke, alcohol abuse, immunodeficiency, and.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 15/19
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Q: What is likely diagnosis for a small child who suffer from stomach pain, vomiting and high fever?
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Prompt → Categories: ['BodyPart', 'DiagnosticTest', 'Symptom'] | Nodes: 5
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Symptom', 'Treatment'] | Nodes: 20
✓ Graph-validated (Valid)
The most probable diagnosis of this small child with stomach pain, vomiting and high fever is Acute gastroenteritis . This condition can be caused by many different pathogens including viruses (e. g. rotavirus), bacteria (e. g. Salmonella), parasites (e. g. Giardia lamblia), fungi (e. g. Candida albicans) and toxins (e. g. Clostridium difficile). It usually presents as acute abdominal pain, nausea and vomiting in children aged between one month to five years old. Diagnosis should be confirmed through laboratory tests such as blood count, urine analysis, stool culture, serology testing and imaging studies like computed tomography scan. Treatment includes rehydration therapy, antibiotics and anti-emetics. Prognosis depends on the underlying cause which may range from complete recovery to death. Chronic diarrhea is characterized by chronic intermittent episodes of loose stools lasting several weeks or months. Common causes are inflammatory bowel disease, celiac disease, irritable bowel syndrome, food allergy, lactose intolerance, cystic fibrosis, primary immunodeficiency disorders, short gut syndrome and intestinal atresia. Differential diagnoses must exclude other conditions that present similar symptoms. Management involves dietary modification, medications and surgery depending on the etiology. Prognosis varies according to the underlying disorder but generally it ranges from complete resolution to severe disability. Intestinal perforation is an uncommon complication of necrotizing enterocolitis
Please consult a healthcare professional for personalized medical advice.
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QUESTION 16/19
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Q: Reasons for feeling low energy and treatment options?
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Prompt → Categories: ['Treatment'] | Nodes: 0
Answer → Categories: ['BodyPart', 'DiagnosticTest', 'Disease', 'RiskFactor', 'Symptom', 'Treatment'] | Nodes: 10
✓ Graph-validated (Valid)
The reasons for a person's feeling of low energy are varied but can be grouped into three categories: Poor nutrition , Chronic disease , and. Physical activity . Treatment options include dietary modification, exercise programs, medications, surgery, and acupuncture. Nutritional support is important because it improves physical function and reduces fatigue. Exercise has been shown to reduce symptoms associated with cancer cachexia; however, many people do not participate in such activities due to barriers including lack of time and fear of injury from exercising too much. Medications have also proven effective at reducing symptoms related to cancer-induced weight loss. Surgery remains one of the most successful methods of improving body composition and overall health status. Acupuncture appears promising as a complementary therapy for treating cancer-related pain and other symptoms. However, further research on its efficacy is needed before this modality should be recommended routinely. Cancer diagnosis , chemotherapy, radiation therapy, surgical procedures, and hormonal therapies all contribute to decreased levels of energy. Dietary modifications, exercise programs, medication management, and surgery.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 17/19
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Q: What are the best treatment options for depression?
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Prompt → Categories: ['Disease', 'Treatment'] | Nodes: 1
Answer → Categories: ['Disease', 'RiskFactor', 'Treatment'] | Nodes: 5
✓ Graph-validated (Valid)
Depression is a common condition that can be treated with medications and psychotherapy. The most effective treatments are antidepressants (selective serotonin reuptake inhibitors) and cognitive behavioral therapy. Other therapies such as electroconvulsive therapy may also help patients who do not respond to other interventions.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 18/19
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Q: What is the ideal daily exercise regiment for elderly with diabetes?
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Prompt → Categories: [] | Nodes: 0
Answer → Categories: ['Disease', 'Treatment'] | Nodes: 3
✓ Graph-validated (No prompt entities)
The recommended exercise regimen for patients with type 2 diabetes should be a combination of aerobic and resistance exercises at least three times per week. Aerobic exercises are performed in an upright position using a stationary bicycle ergometer or treadmill while resisted leg presses (squats) and knee extensions are done on a Smith machine. Resistance training includes both lower-body muscle groups as well as upper-body muscles.
Please consult a healthcare professional for personalized medical advice.
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QUESTION 19/19
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Q: Is arsenic acid safe to drink?
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Prompt → Categories: [] | Nodes: 0
Answer → Categories: ['BodyPart', 'Disease', 'Riskfactor', 'Treatment'] | Nodes: 2
✓ Graph-validated (No prompt entities)
Arsenic is a toxic metalloid that can cause acute and chronic health effects when ingested in high doses. It has been used for centuries as an antidote against snake bites and other poisonous animals. In recent years it has also become popular among the general public due to its potential use as a treatment for cancer. However, there are concerns about its safety because of reports of adverse events including death from ingestion. The American Academy of Pediatrics recommends withholding arsenic therapy until further research clarifies its risks and benefits.
Please consult a healthcare professional for personalized medical advice.
Medical AI as Co-Pilot for Students
byu/vagobond45 inFuturology