Researchers use CRISPR to “unlock” immune cells’ power against solid tumors. In a mouse study, researchers found they can use CRISPR to delete a gene called FLI1 to enhance human killer cell survival after tumor infiltration.

https://www.uclahealth.org/news/release/ucla-researchers-use-crispr-unlock-immune-cells-power

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  1. UCLA researchers use CRISPR to “unlock” immune cells’ power against solid tumors

    In a mouse study, researchers found they can use CRISPR to delete a gene called FLI1 to enhance human killer cell survival after tumor infiltration

    A UCLA-led research team has identified a genetic “brake” that prevents the body’s natural defense system from attacking solid tumors. By using CRISPR technology to delete a specific gene called FLI1, researchers were able to significantly enhance the ability of Natural Killer (NK) cells to survive and inhibit solid tumor growth.

    For those interested, here’s the link to the peer reviewed journal article:

    https://www.cell.com/immunity/abstract/S1074-7613(26)00035-X