Certain types of antibiotics can be linked to changes in the gut microbiome as long as four to eight years after treatment

https://www.uu.se/en/press/press-releases/2026/2026-03-11-antibiotics-can-affect-the-gut-microbiome-for-several-years

6 Comments

  1. >In the study, the researchers analysed drug register data alongside a detailed mapping of the gut microbiome of 14,979 adults living in Sweden. The gut microbiome was compared between participants who had received different types of antibiotics and those who had not received any at all during the period

    > **The researchers found that the results differed substantially depending on the type of antibiotic used.** The strongest associations were observed for clindamycin, fluoroquinolones and flucloxacillin. By contrast, penicillin V, the most commonly prescribed antibiotic for the treatment of infections outside hospitals in Sweden, was linked to small and short-lasting microbiome changes.

    [Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals | Nature Medicine](https://www.nature.com/articles/s41591-026-04284-y)

  2. Would taking probiotics alongside antibiotics offset the impacts of antibiotics on the gut microbiome?

  3. I think there’s a lot to be learned about our gut bacteria. I think the idea of fecal transplants is fascinating. And I know there are two FDA approved treatments, Rebyota and Vowst. I assume they’ve been shown to be Safe and effective.

  4. Business_Cake_2272 on

    Is there any way of speeding up recovery? Would a diet high in fiber and super diverse possibly help? Or not really?

  5. alex_eternal on

    I wonder how this might correlate to individuals who have been diagnosed with some form of colon cancer in their lifetime. Since that is now the most prevalent cause of death for millennials.

  6. crohnscyclist on

    clarithromycin triggered a Crohn’s flare almost instantly in me that started in early April, sent me to the hospital by late June, removal of my entire large colon by mid July and followed up with complications that left me down to skin and bones, nearly 35% reduction in weight.

    I wish I would have just suffered through the chest infection.