They will be facing Estonia and Finland at Donard Park in Newcastle.
The tri-nations tournament is being supported by Newry, Mourne and Down District Council.
Head coach Michael McClean has chosen a 20-strong squad for the matches in Co Down, with the bulk of the players coming from the Irish FA JD Academy (residential and non-residential).
Game one in the tournament will see Northern Ireland play Estonia at Donard Park next Monday (14 September). The match is due to kick off at 2pm.
On Wednesday 16 September Estonia will be in action again, this time against Finland (12pm).
The final game of the tournament is pencilled in for Friday 18 September when Northern Ireland will face the Finns (11am start).
And there is free entry to all three matches at Donard Park.
The Northern Ireland U16s squad for the tri-nations tournament in Newcastle is as follows:
Goalkeepers – Cuan O’Bradaigh (Cliftonville), Harry McSwiney (Derry City).
Defenders – Luca Lavery (Glentoran), Eoin McCann (Cliftonville), Daithi Holleran (Linfield), Cohen Ennis (Glentoran), Shea Donnelly (Ballinamallard United), Gus Murdock (Manchester United), Riley McCreery (Cliftonville), Corey McCartney (Linfield).
Midfielders – Calum Evans (Linfield), Rylan Heaney (Norwich City), Will Davison (Dungannon Swifts), Quinn Milligan (Linfield), Corey Harkin (Derry City), Alfie Davidson (Glentoran).
Forwards – Eoghan Mallon (Loughgall), Ryland Perry (Cliftonville), Dara Donnan (Linfield), Conleth O’Neill (Linfield).