> Researchers at UC Davis have fiddled with LSD at the atomic level and may have unlocked a potential game-changing treatment for schizophrenia. The new compound, known as JRT, might be able to repair the brain without making you trip balls.
> The scientists were toying with LSD atoms when they decided to, in their own words, do a “tire rotation.” This meant swapping the position of two atoms in LSD’s molecular structure. That tiny change turned it from a powerful hallucinogen into something that can **regrow brain cells in mice and mend neural pathways without launching your consciousness into the cosmos**
> JRT managed to reduce the negative symptoms of schizophrenia in mice, like cognitive fog and social withdrawal, without triggering the kind of psychosis you really don’t want in people already dealing with psychosis.
> UC Davis chem professor David Olson said JRT could eventually offer a safer, more targeted alternative to current meds like clozapine, which come with side effects like emotional numbness and cognitive decline. This comes after it’s been shown that LSD might also help with anxiety.
0vert0ady on
Remember when they said the same thing about synthetic cannabis? Lets hope they ain’t wrong this time.
hyperdream on
Later to be retracted when it’s found that there were no mice, there is no breakthrough…. they’d just been synthesizing and taking LSD for a couple of years, so now they live in a completely different reality.
yahwehforlife on
How tf do you measure schizophrenic symptoms in mice??
Future-self on
I wonder if this can help tinnitus or fibromyalgia ??
EatAllTheShiny on
In mice.
Let me know when it works on human brain tissue, let alone actual humans.
There’s about a 10% real world conversion of things-that-work-on-mice and things-that-work-the-same-way-on-humans.
EmphasisFull5182 on
I just hope it won’t be forgotten like the plastic eating bacteria. Or the salt batteries.
oldmilt21 on
That’s not what happened when I messed around with it.
Begrudged_Registrant on
I’m gonna call this ‘Diet Acid’, and you can’t make me stop.
NeurogenesisWizard on
Now study it with the entourage effect (LSD in combination with JRT)
ExoticCard on
I know the grad students in that lab have already taken it themselves
superwillis on
This is great if it works. But…I remain skeptical. I have taken many psychedelic substances in my past. My skepticism is mainly because of this ever-present desire in pop science to somehow utilize the benefits of these drugs without “tripping”, which is viewed as a negative side effect. But I strongly feel like the trip and the subjective experience are a very vital part of any healing. It’s not “magically” changing neuronal connections without you subjectively realizing it’s happening ( like a beta blocker or a statin), the changes are from the experience, just like any other. it’s mostly giving you a crazy experience which leads to insights and that is what helps change you. It changes your reality for a bit. In the same way that traveling to a brand new foreign country and meeting unique people might change your outlook on life. Hence the term “trip”.
12 Comments
> Researchers at UC Davis have fiddled with LSD at the atomic level and may have unlocked a potential game-changing treatment for schizophrenia. The new compound, known as JRT, might be able to repair the brain without making you trip balls.
> The scientists were toying with LSD atoms when they decided to, in their own words, do a “tire rotation.” This meant swapping the position of two atoms in LSD’s molecular structure. That tiny change turned it from a powerful hallucinogen into something that can **regrow brain cells in mice and mend neural pathways without launching your consciousness into the cosmos**
> JRT managed to reduce the negative symptoms of schizophrenia in mice, like cognitive fog and social withdrawal, without triggering the kind of psychosis you really don’t want in people already dealing with psychosis.
> UC Davis chem professor David Olson said JRT could eventually offer a safer, more targeted alternative to current meds like clozapine, which come with side effects like emotional numbness and cognitive decline. This comes after it’s been shown that LSD might also help with anxiety.
Remember when they said the same thing about synthetic cannabis? Lets hope they ain’t wrong this time.
Later to be retracted when it’s found that there were no mice, there is no breakthrough…. they’d just been synthesizing and taking LSD for a couple of years, so now they live in a completely different reality.
How tf do you measure schizophrenic symptoms in mice??
I wonder if this can help tinnitus or fibromyalgia ??
In mice.
Let me know when it works on human brain tissue, let alone actual humans.
There’s about a 10% real world conversion of things-that-work-on-mice and things-that-work-the-same-way-on-humans.
I just hope it won’t be forgotten like the plastic eating bacteria. Or the salt batteries.
That’s not what happened when I messed around with it.
I’m gonna call this ‘Diet Acid’, and you can’t make me stop.
Now study it with the entourage effect (LSD in combination with JRT)
I know the grad students in that lab have already taken it themselves
This is great if it works. But…I remain skeptical. I have taken many psychedelic substances in my past. My skepticism is mainly because of this ever-present desire in pop science to somehow utilize the benefits of these drugs without “tripping”, which is viewed as a negative side effect. But I strongly feel like the trip and the subjective experience are a very vital part of any healing. It’s not “magically” changing neuronal connections without you subjectively realizing it’s happening ( like a beta blocker or a statin), the changes are from the experience, just like any other. it’s mostly giving you a crazy experience which leads to insights and that is what helps change you. It changes your reality for a bit. In the same way that traveling to a brand new foreign country and meeting unique people might change your outlook on life. Hence the term “trip”.
I am a doctor and did go to medical school, fwiw.