New research provides preliminary evidence that whole-body hyperthermia shows promising antidepressant effects through anti-inflammatory pathways
Whole-body hyperthermia shows promising antidepressant effects through anti-inflammatory pathways
New research provides preliminary evidence that whole-body hyperthermia shows promising antidepressant effects through anti-inflammatory pathways
Whole-body hyperthermia shows promising antidepressant effects through anti-inflammatory pathways
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From the article: The findings have been published in the journal [Brain, Behavior, and Immunity](https://www.sciencedirect.com/science/article/pii/S088915912400388X).
Depression is a leading cause of disability worldwide and is expected to become the largest contributor to global disease burden by 2030. Despite the availability of various antidepressant treatments, their effectiveness remains limited for many individuals. This has driven researchers to explore alternative treatments and better understand their mechanisms.
Previous research indicated that fever-range whole-body hyperthermia could produce rapid and sustained antidepressant effects, but the underlying biological mechanisms remained unclear. Whole-body hyperthermia involves raising the body’s core temperature to therapeutic levels, typically through methods such as infrared heat. This process induces a fever-like state, which can activate various physiological responses.
Damn should i try and make myself sick somehow
Time to jump in the sauna
“Well, shock therapy ended up a mixed bag that ultimately wasn’t as widely accepted as we anticipated. Any other ideas? Keep in mind that bloodletting, cocktails made from the excretions of random animals, and screaming Bible verses in the face of someone strapped to chair have already been used and found rather unsuccessful.”
“What if we slowly heat their entire body to almost the point of death?”
(Edit: originally misread as Hypothermia)
Could this be a tertiary benefit of exercise? In the article they mention raising body temp to ~38.5c for a short period, Google says body temp can spike up to ~40c during strenuous exercise, and raises ~1-3c during normal exercise. That would put people around 38c for moderate exercise, it seems.
Is this why standing in a hot shower with water pouring down your head helps?
In your face cold plunge people. I’m off to the sauna.