Data Skrive
The San Francisco Giants and Rafael Devers head into the first of a three-game series against Fernando Tatis Jr. and the San Diego Padres on Monday at Oracle Park. The Padres have been listed as +120 moneyline underdogs for this matchup with the Giants (-141). San Francisco (-1.5) is the favorite on the run line. The over/under is 7.5 runs for this game (with -110 odds on the over and -110 odds on the under).
Take a look at everything you need from a betting perspective on the Giants-Padres game, regarding the run line, moneyline and total, plus expert picks.
Keep up with MLB on FOX Sports.
Check out the best highlights between the Washington Nationals and San Francisco Giants.
Giants vs. Padres Game Information & Odds
- When: Monday, August 11, 2025 at 9:45 p.m. ET
- Where: Oracle Park in San Francisco, California
- How to watch on TV: NBCS-BA and SDPA
Giants vs. Padres Prediction
- Score Prediction: Giants 5, Padres 4
- Total Prediction: Over 7.5 runs
- Win Probabilities: Giants 52%, Padres 48%
Giants vs. Padres Betting Insights
- The Giants have entered the game as favorites 72 times this season and won 37, or 51.4%, of those games.
- San Francisco has entered 48 games this season favored by -141 or more and is 25-23 in those contests.
- The implied probability of a win from the Giants, based on the moneyline, is 58.5%.
- The Padres have won in 27, or 50.9%, of the 53 contests they have been named as odds-on underdogs this year.
- This season, San Diego has been victorious 13 times in 28 chances when named as an underdog of at least +120 or worse on the moneyline.
- Bookmakers have implied with the moneyline set for this matchup that the Padres have a 45.5% chance of pulling out a win.
Giants Recent Betting Performance
- The Giants went 3-4 over the seven games they were favored on the moneyline in their last 10 matchups.
- In their last 10 matchups, the Giants and their opponents combined to hit the over four times (all 10 of the games had set totals).
- The Giants are 5-5-0 against the spread over their past 10 games.
Giants Recent Stats
Giants Player Insights
- Devers leads the Giants with 22 home runs and 80 runs batted in.
- In all of the majors, Devers ranks 25th in homers and ninth in RBI.
- Jung Hoo Lee is batting .256 with 27 doubles, nine triples, six home runs and 38 walks.
- Lee is 238th in home runs in the majors, and 115th in RBI.
- Willy Adames is hitting .229 with 18 doubles, two triples, 18 home runs and 55 walks.
- Heliot Ramos is batting .273 to lead his team.
- Ramos is riding a two-game hitting streak into this one. During his last five outings he is batting .300 with three walks.
Padres Recent Betting Performance
- Over the past 10 games, bookmakers have not installed the Padres as underdogs once.
- In their last 10 games with a total, the Padres and their opponents are 6-4-0 when it comes to hitting the over.
- Over their last 10 games, the Padres are 5-5-0 against the spread.
Padres Recent Stats
Padres Player Insights
- Manny Machado paces the Padres with 20 home runs and 72 runs batted in, while recording a team-best batting average of .297.
- Among all hitters in the big leagues, Machado’s home run total is 37th and his RBI tally ranks 19th.
- Tatis is batting .262 with 19 doubles, two triples, 17 home runs and 66 walks.
- Tatis is 62nd among all hitters in MLB in home runs, and 115th in RBI.
- Luis Arraez is hitting .295 with 23 doubles, four triples, six home runs and 24 walks.
- Xander Bogaerts has 25 doubles, 10 home runs and 46 walks while batting .271.
Check out the best highlights between the Washington Nationals and San Francisco Giants.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.
recommended
Arrow pointing to the leftArrow pointing to the right
Item 1 of 2