Carpenter, B. D., Gatz, M. & Smyer, M. A. Mental health and aging in the 2020s. Am. Psychol. 77, 538–550 (2022).
Abdoli, N. et al. The global prevalence of major depressive disorder (MDD) among the elderly: a systematic review and meta-analysis. Neurosci. Biobehav. Rev. 132, 1067–1073 (2022).
Cheng, Y. et al. The burden of depression, anxiety and schizophrenia among the older population in ageing and aged countries: an analysis of the Global Burden of Disease Study 2019. Gen. Psychiatr. 37, e101078 (2024).
Steffens, D. C. Late-life depression, antidepressant treatment, and cognition: the short haul and the long haul. Am. J. Psychiatry 181, 183–185 (2024).
Taylor, W. D. et al. Reconsidering remission in recurrent late-life depression: clinical presentation and phenotypic predictors of relapse following successful antidepressant treatment. Psychol. Med. 54, 4896–4907 (2024).
Alexopoulos, G. S. Mechanisms and treatment of late-life depression. Focus 19, 269–378 (2021).
Davies, K., Maharani, A., Chandola, T., Todd, C. & Pendleton, N. The longitudinal relationship between loneliness, social isolation, and frailty in older adults in England: a prospective analysis. Lancet Healthy Longev. 2, e70 (2021).
Peverill, M. et al. Socioeconomic status and child psychopathology in the United States: a meta-analysis of population-based studies. Clin. Psychol. Rev. 83, 101933 (2021).
Cai, J. et al. Socioeconomic status, individual behaviors and risk for mental disorders: a Mendelian randomization study. Eur. Psychiatry 65, e28 (2022).
Lai, E. T. C., Ho, S. C. & Woo, J. Social isolation, socioeconomic status, and development of functional impairments in Chinese older adults aged 70 years and over: a cohort study. Aging Clin. Exp. Res. 35, 155–165 (2023).
Evans, G. W. & France, K. D. Childhood poverty and psychological well-being: the mediating role of cumulative risk exposure. Dev. Psychopathol. 34, 911–921 (2022).
Kirkbride, J. B. et al. The social determinants of mental health and disorder: evidence, prevention and recommendations. World Psychiatry 23, 58 (2024).
Islam, S. & Jaffee, S. R. Social mobility and mental health: a systematic review and meta-analysis. Soc. Sci. Med 340, 116340 (2024).
Hallqvist, J., Lynch, J., Bartley, M., Lang, T. & Blane, D. Can we disentangle life course processes of accumulation, critical period and social mobility? An analysis of disadvantaged socio-economic positions and myocardial infarction in the Stockholm Heart Epidemiology Program. Soc. Sci. Med. 58, 1555–1562 (2004).
Remes, O., Mendes, J. F. & Templeton, P. Biological, psychological, and social determinants of depression: a review of recent literature. Brain Sci. 11, 1633 (2021).
Kim, H., Bae, E. J., Choi, Y. & Son, H. Biopsychosocial factors of quality of life among middle-aged adults living alone in South Korea: a secondary data analysis using the 2017 Korea Community Health Survey. Arch. Public Health 82, 108 (2024).
Panza, F. et al. Depressive and biopsychosocial frailty phenotypes: impact on late-life cognitive disorders. J. Alzheimers. Dis. 94, 879–898 (2023).
Lian, Y., Yang, L., Gao, M. & Jia, C.-X. Relationship of frailty markers and socioeconomic status to incidence of depressive symptoms in a community cohort. J. Am. Med. Dir. Assoc. 22, 570–576.e1 (2021).
Hanlon, P. et al. The relationship between frailty and social vulnerability: a systematic review. Lancet Healthy Longev. 5, e214 (2024).
Zhan, Y., Zhan, X. & Wu, M. From financial assistance to emotional care: the impact of intergenerational support on the subjective well-being of China’s elderly. J. Happiness Stud. 26, 17 (2025).
Pan, C. & Cao, N. Patterns of social isolation and low social support and frailty trajectories among Chinese older adults. J. Appl. Gerontol. 42, 2325–2334 (2023).
Gheorghe, A.-C. et al. Frailty and loneliness in older adults: a narrative review. Geriatrics 9, 119 (2024).
Wang, Y. et al. The associations of socioeconomic status, social activities, and loneliness with depressive symptoms in adults aged 50 years and older across 24 countries: findings from five prospective cohort studies. Lancet Healthy Longev. 5, 100618 (2024).
Zhang, Z., Xu, H., Zhou, J. & Cao, X. The impact of mold exposure on anxiety symptoms in the older adults: a moderated mediation model based on CLHLS. Ecotoxicol. Environ. Saf. 284, 116967 (2024).
Xu, H., Zhang, Z. & Hua, L. Urban resilience reduces depressive symptoms among middle-aged and elderly adults: a multidimensional analysis based on China longitudinal healthy longevity survey. J. Psychiatr. Res 178, 250–258 (2024).
Noushad, S. et al. Physiological biomarkers of chronic stress: a systematic review. Int J. Health Sci. 15, 46–59 (2021).
Morrissey, K. & Kinderman, P. The impact of childhood socioeconomic status on depression and anxiety in adult life: testing the accumulation, critical period and social mobility hypotheses. SSM Popul. Health 11, 100576 (2020).
Liu, J., Yu, M. & Zhang, T. Age-friendly neighborhood environment and trajectories of multimorbidity: the moderating effect of life-course socioeconomic status. Innov. Aging 9, igaf039 (2025).
Pan, T., Li, C. & Zhou, Y. Life course socioeconomic position and care dependency in later life: a longitudinal multicohort study from 17 countries. EClinicalMedicine 79, 102994 (2025).
Wang, Y. et al. Life course patterns of work history and cognitive trajectories among community-dwelling older adults. J. Gerontol. B 80, gbae195 (2025).
Xue, Y. et al. The relationship between socioeconomic status and depression among the older adults: the mediating role of health promoting lifestyle. J. Affect. Disord. 285, 22–28 (2021).
Liu, Y., Liu, Z., Liang, R. & Luo, Y. The association between community-level socioeconomic status and depressive symptoms among middle-aged and older adults in China. BMC Psychiatry 22, 297 (2022).
Domènech-Abella, J. et al. From childhood financial hardship to late-life depression: socioeconomic pathways. Aging Ment. Health 25, 86–93 (2021).
Li, W., Liu, E., Balezentis, T., Jin, H. & Streimikiene, D. Association between socioeconomic welfare and depression among older adults: evidence from the China Health and Retirement Longitudinal Study. Soc. Sci. Med. 275, 113814 (2021).
Gabriel, A. et al. Evaluating depressive symptoms among low-socioeconomic-status African American women aged 40 to 75 years with uncontrolled hypertension: a secondary analysis of a randomized clinical trial. JAMA Psychiatry 78, 426–432 (2021).
Ye, C., Ye, B. & Zhang, Z. The relationship between unpredictability in childhood and depression among college students: the mediating roles of coping style and resilience. BMC Psychol. 12, 333 (2024).
Wilkinson, R. G. in Class and Health (ed. Wilkinson, R. G.) Ch. 1 (Routledge, 1986).
He, S. & Stein, A. D. Early-life nutrition interventions and associated long-term cardiometabolic outcomes: a systematic review and meta-analysis of randomized controlled trials. Adv. Nutr. 12, 461–489 (2021).
Deutscher, N. & Mazumder, B. Measuring intergenerational income mobility: a synthesis of approaches. J. Econ. Lit. 61, 988–1036 (2023).
Nazri, N. S., Vanoh, D. & Leng, S. K. Malnutrition, low diet quality and its risk factors among older adults with low socio-economic status: a scoping review. Nutr. Res. Rev. 34, 107–116 (2021).
Howlett, S. E., Rutenberg, A. D. & Rockwood, K. The degree of frailty as a translational measure of health in aging. Nat. Aging 1, 651–665 (2021).
Zhou, Y. & Ma, L. Intrinsic capacity in older adults: recent advances. Aging Dis. 13, 353–359 (2022).
Sun, R. & Zhang, Z. Leisure activities and cognitive impairment in old age: the role of life course socioeconomic status. Aging Ment. Health 27, 326–333 (2023).
Cao, Q., Dabelko-Schoeny, H. I., White, K., Maleku, A. & Sheldon, M. I wanna help, but my hands can be a little tied: the challenges and benefits of formal volunteering among low-income diverse older adults. J. Gerontol. Soc. Work 64, 388–404 (2021).
Wang, S. et al. Risk factors for social isolation in older adults: a systematic review and meta-analysis. Public Health Nurs. 41, 200–208 (2024).
Crielaard, L., Nicolaou, M., Sawyer, A., Quax, R. & Stronks, K. Understanding the impact of exposure to adverse socioeconomic conditions on chronic stress from a complexity science perspective. BMC Med. 19, 242 (2021).
Zhang, Y., Su, D., Chen, Y., Tan, M. & Chen, X. Effect of socioeconomic status on the physical and mental health of the elderly: the mediating effect of social participation. BMC Public Health 22, 605 (2022).
Longoria, K. D. et al. A sum of its parts: a systematic review evaluating biopsychosocial and behavioral determinants of perinatal depression. PLoS ONE 19, e0290059 (2024).
Chow, T. K. et al. Contributors of functional impairment in major depressive disorder: a biopsychosocial approach. Curr. Behav. Neurosci. Rep. 9, 59–72 (2022).
Li, S. & Xu, Q. Family support as a protective factor for attitudes toward social distancing and in preserving positive mental health during the COVID-19 pandemic. J. Health Psychol. 27, 858–867 (2022).
Hostinar, C. E. & Gunnar, M. R. Social support can buffer against stress and shape brain activity. AJOB Neurosci. 6, 34–42 (2015).
Xu, H. in Encyclopedia of Gerontology and Population Aging (eds Gu, D. & Dupre, M. E.) 1132–1135 (Springer, 2021); https://doi.org/10.1007/978-3-030-22009-9_998
Twenge, J. M. & Campbell, W. K. Cultural individualism is linked to later onset of adult-role responsibilities across time and regions. J. Cross-Cult. Psychol. https://doi.org/10.1177/0022022118764838 (2018).
Falzarano, F., Moxley, J., Pillemer, K. & Czaja, S. J. Family matters: cross-cultural differences in familism and caregiving outcomes. J. Gerontol. B 77, 1269–1279 (2021).
Purgato, M. et al. Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries. Cochrane Database Syst. Rev. 2023, CD014722 (2023).
Lee, H., Park, S. & Kwon, E. Life course pathway to later-year depressive symptoms: multiple mediation of socio-economic status and coping resources by gender. Res. Aging 43, 237–249 (2021).
Ran, G., Zuo, C. & Liu, D. Negative wealth shocks and subsequent depressive symptoms and trajectories in middle-aged and older adults in the USA, England, China, and Mexico: a population-based, multinational, and longitudinal study. Psychol. Med. 54, 3888–3895 (2024).
Ruiz, M., Hu, Y., Martikainen, P. & Bobak, M. Life course socioeconomic position and incidence of mid–late life depression in China and England: a comparative analysis of CHARLS and ELSA. J. Epidemiol. Community Health 73, 817–824 (2019).
Williams, D. R. The health of men: structured inequalities and opportunities. Am. J. Public Health https://doi.org/10.2105/AJPH.98.Supplement_1.S150 (2011).
Inglis, V., Ball, K. & Crawford, D. Why do women of low socioeconomic status have poorer dietary behaviours than women of higher socioeconomic status? A qualitative exploration. Appetite 45, 334–343 (2005).
Hossen, M. S. & Salleh, S. F. B. Social influences on the psychological well-being of elderly individuals. J. Humanit. Appl. Soc. Sci. 7, 315–332 (2025).
Fang, Y., Chau, A. K. C., Wong, A., Fung, H. H. & Woo, J. Information and communicative technology use enhances psychological well-being of older adults: the roles of age, social connectedness, and frailty status. Aging Ment. Health 22, 1516–1524 (2018).
DeCarlo Santiago, C., Wadsworth, M. E. & Stump, J. Socioeconomic status, neighborhood disadvantage, and poverty-related stress: prospective effects on psychological syndromes among diverse low-income families. J. Econ. Psychol. 32, 218–230 (2011).
Luo, J., Zhang, B., Antonoplis, S. & Mroczek, D. K. The effects of socioeconomic status on personality development in adulthood and aging. J. Pers. 92, 243–260 (2024).
Umberson, D., Thomeer, M. B. & Williams, K. in Handbook of the Sociology of Mental Health (eds. Aneshensel, C. S. et al.) 405–431 (Springer, 2013); https://doi.org/10.1007/978-94-007-4276-5_20
Cleary, J. L. et al. Polygenic risk and social support in predicting depression under stress. Am. J. Psychiatry 180, 139–145 (2023).
Torres, J. M., Rizzo, S. & Wong, R. Lifetime socioeconomic status and late-life health trajectories: longitudinal results from the Mexican Health and Aging Study. J. Gerontol. B 73, 349–360 (2018).
Zhou, S. et al. Association of cumulative average sensory impairments with cognitive function and depressive symptoms: two prospective cohort studies. J. Affect. Disord. 369, 16–24 (2025).
Yan, R. et al. Association between internet exclusion and depressive symptoms among older adults: panel data analysis of five longitudinal cohort studies. eClinicalMedicine 75, 102767 (2024).
Torres, J. M. & Wong, R. Childhood poverty and depressive symptoms for older adults in Mexico: a life-course analysis. J. Cross-Cult. Gerontol. 28, 317–337 (2013).
Li, R. et al. Associations of socioeconomic status and healthy lifestyle with incident early-onset and late-onset dementia: a prospective cohort study. Lancet Healthy Longev. 4, e693 (2023).
Tang, L., Yin, R., Hu, Q., Fan, Z. & Zhang, F. The effect of childhood socioeconomic status on depressive symptoms in middle-old age: the mediating role of life satisfaction. BMC Psychiatry 22, 398 (2022).
Ye, X., Zhu, D. & He, P. Direct and indirect associations between childhood socioeconomic status and cognitive function in the middle-aged and older adults in China. Aging Ment. Health 26, 1730–1737 (2022).
McElroy, E. et al. Influence of childhood socioeconomic position and ability on mid-life cognitive function: evidence from three British birth cohorts. J. Epidemiol. Community Health 75, 643–650 (2021).
Wang, D. et al. Association between socioeconomic status and health behaviour change before and after non-communicable disease diagnoses: a multicohort study. Lancet Public Health 7, e670 (2022).
Wang, K. et al. Associations of socioeconomic status and healthy lifestyle with incident dementia and cognitive decline: two prospective cohort studies. eClinicalMedicine 76, 102831 (2024).
He, D. et al. Changes in frailty and incident cardiovascular disease in three prospective cohorts. Eur. Heart J. 45, 1058–1068 (2024).
Li, L. Internet use and frailty in middle-aged and older adults: findings from developed and developing countries. Glob. Health 20, 53 (2024).
Fan, J. et al. Frailty index and all-cause and cause-specific mortality in Chinese adults: a prospective cohort study. Lancet Public Health 5, e650 (2020).
Zhou, J. The dataset of article ‘Linking socioeconomic status to depressive symptoms in aging populations’. Zenodo https://zenodo.org/records/17206621 (2025).
Zhou, J. The code of article ‘Linking socioeconomic status to depressive symptoms in aging populations’. Zenodo https://zenodo.org/records/17206818 (2025).
