First hormone-free male birth control pill clears another milestone – In male mice, the drug caused infertility and was 99% effective in preventing pregnancies within four weeks of use. In male non-human primates, the drug lowered sperm counts within two weeks of starting the drug.
https://twin-cities.umn.edu/news-events/first-hormone-free-male-birth-control-pill-clears-another-milestone
9 Comments
First hormone-free male birth control pill clears another milestone
While the FDA has approved over 20 different categories of contraceptives, only two are available for men to prevent pregnancy in their partners — condoms and vasectomies. 25% of women who use contraception use an oral birth control pill, but there are no equivalent methods currently available for men.
Research from the University of Minnesota College of Pharmacy, published in Communications Medicine, laid the groundwork for the first hormone-free male birth control pill to enter clinical trials.
The new drug, called YCT-529, is a first-in-class, hormone-free and orally administered male contraceptive. Developed in collaboration with Columbia University in New York and YourChoice Therapeutics, YCT-529 works as a contraceptive by stopping the production of sperm.
The research found:
– In male mice, the drug caused infertility and was 99% effective in preventing pregnancies within four weeks of use.
– In male non-human primates, the drug lowered sperm counts within two weeks of starting the drug.
– Both mice and non-human primates fully regained fertility after stopping the drug. Mice regained fertility within six weeks, and non-human primates fully recovered their sperm count in 10-15 weeks.
– No side effects from the drug were detected in either group.
they already have this, it’s called HRT. you can inject estrogen without any anti-androgens and be infertile within 4 weeks 🙂
why would you want to be infertile?
downvote me/ban me from this machine
Hormone free? Yeah that’s bullshit.
Also what did it do to test levels while on it?
If I read my administrations right, if this comes to market soon, then 1) only the wealthy will be able to afford it, or 2) it will outlawed altogether. Can’t have those beneath the one percent NOT providing a steady flow of slave labor!
Personally I would never take a drug that stopped one of my bodies natural function, it just doesn’t sit right with me at all. Messing around with how your body functions cannot be good for you. I have read many stories about women having awful problems after using the pill, it just seems wrong to stop your body doing what it should be doing. Each to their own but definitely not for me.
Millions of dollars of research just to avoid the snip snip. Tragic
Here’s hoping this quietly vanishes into whatever void all the other miracle headline drugs end up in. Population collapse is already looking like it’ll be bad enough without this stuff.
I’m a bit late to this party. Vasectomy has its magic done on my end. Still really cool to see these making it this far. How long until it’s affordable, accessible, and getting blamed for declining birth rates?
“They” will take away the existing birth control first, most likely, if it comes to that. Without getting into the politics too deep, I do wonder if it becomes an issue there.
All the dudes here protesting male non-hormonal birth control don’t understand the side effects of “the pill”.
Look up the “Major Histocompatibility Complex”.
It’s key in determining who we’re attracted to. Female hormonal birth control can significantly alter the natural selection process.
Women on hormonal contraceptives often choose partners with similar genetic makeup instead of complementary ones.
When they stop taking the pill, they might find themselves suddenly less attracted to their partner.
The research shows women naturally prefer the scent of men with different immune systems than their own when not on hormonal birth control. [Sauce.](https://pmc.ncbi.nlm.nih.gov/articles/PMC2605820/)
This isn’t just a minor side effect. It fundamentally changes mate selection processes that evolved over thousands of years.
Some studies suggest women partnered with men they met while on the pill report less sexual satisfaction and are more likely to initiate breakups when they discontinue use.
So before y’all start complaining about potential side effects of male birth control, remember that women have been dealing with contraceptives that literally rewire their attraction patterns for decades.
Not to mention the other side effects like depression, blood clots, and weight gain that come standard.
Seems like a pretty reasonable tradeoff to have non-hormonal options available to men that don’t mess with their entire sense of who they are & want to be with.