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  1. Submission Statement:

    YCT-529, a hormone-free male birth control pill, has shown high effectiveness in animals and is now in human trials, marking a breakthrough in male contraception.

    While the FDA has approved more than 20 types of contraceptives, only two options currently exist for men: condoms and vasectomies. Although about 25% of women who use contraception rely on the oral birth control pill, there is no equivalent pill available for men.

    However, research from the University of Minnesota College of Pharmacy, published in Communications Medicine, has paved the way for the first hormone-free male birth control pill to reach clinical trials.

    This new drug, YCT-529, is an innovative, hormone-free, orally administered contraceptive designed for men. Developed in partnership with Columbia University and YourChoice Therapeutics, YCT-529 prevents pregnancy by inhibiting sperm production.

    The research found:

    In male mice, the drug caused infertility and was 99% effective in preventing pregnancies within four weeks of use.

    In male non-human primates, the drug lowered sperm counts within two weeks of starting the drug.

    Both mice and non-human primates fully regained fertility after stopping the drug. Mice regained fertility within six weeks, and non-human primates fully recovered their sperm count in 10-15 weeks.

    No side effects from the drug were detected in either group.

  2. Trip_like_Me on

    Useless for me as I got a vasectomy but I’m cheering for all the success for this so my brothers that don’t want to take that permanent step can get a viable solution when they want to pause but not eliminate the possibility of having kids. Fingers crossed!

  3. TopInevitable4013 on

    Yet there are a ton of men who will not get a vaccine? Do we really think men will take responsibility for contraception? Some will, but the majority that may not be educated and have not thought-out the consequences of life, that is a stretch.

  4. ThinNeighborhood2276 on

    This could be a game-changer for contraceptive options and gender equality in family planning.

  5. AndarianDequer on

    I was reading about this 20 years ago. Why is it only just now going into trials?

  6. Someone convince RFKjr that this gives you more girth and he’ll make sure it’s put into the water supply.

  7. Theonlyrational on

    I will believe it when it comes to market. This idea has been medical vaporware so far.

  8. Goddamn get this thing out to the public before i fuck around and impregnate my wife again

  9. you_got_my_belly on

    I suspect some shady men, who hate using condoms, will claim they took this pill, as a means to have sex without a condom. Something they hate using, those type of people could care less if it results in a pregnancy.