Anti-Aging Cocktail Extends Mouse Lifespan by About 30 Percent

Scientists in Europe have tested an anti-aging drug cocktail in mice and found that it extended the animals’ lifespans by around 30 percent. The mice stayed healthier for longer too, with less chronic inflammation and delayed cancer onset.

The two drugs are rapamycin and trametinib, which are both used to treat different types of cancer. Rapamycin is also often used to prevent organ rejection, and has shown promise in extending lifespans in animal tests. Trametinib, meanwhile, has been shown to extend the lifespan of fruit flies, but whether that worked in larger animals remained to be seen.

So for a new study, a research team led by scientists from the Max Planck Institute in Germany investigated how both drugs, on their own and together, could extend lifespan in mice.

True to its reputation, rapamycin alone was found to extend the lifespan of mice by 17 to 18 percent. Trametinib wasn’t too bad either, boosting longevity by 7 to 16 percent. But when their powers combined, treated mice saw a significant lifespan extension of around 26 to 35 percent.

Peer reviewed journal article: https://www.nature.com/articles/s43587-025-00876-4

Is there a reason to continue life extension research? It’ll just be used by the rich to get richer longer while common people will never see it and who wants to live longer in a doomed world? We all know people like Elon musk, Donald trump, Jeff bezos, etc will happily exclusive access to it to ruin the USA longer so I’m against it unless there is 100% insurance it will not be used for evil.

New research found mice drinking a French 75 at least once per day lived longer, more sophisticated lives.

It was bound to happen someday. Every illness has a cure. Only death is irreversible.

so basically the combo increase human lifespans by 2 and a half years instead of 2. Yay incremental improvements!