Previous studies show that transfusions of blood or plasma from young mice improved cognitive decline in older mice. In a new study, scientists produced “young” immune cells from human stem cells and when they were infused into mice, they reversed signs of aging and Alzheimer’s disease in the brain.

‘Young’ Immune Cells Could Treat Alzheimer’s, Aging Symptoms

“Young” immune cells created by Cedars-Sinai **investigators reversed signs of aging and Alzheimer’s disease in the brains of laboratory mice**, according to a study published in the journal Advanced Science. **The immune cells, which were produced from human stem cells**, could be used to develop new treatments for neurological conditions in humans.

**Previous studies have shown that transfusions of blood or plasma from young mice improved cognitive decline in older mice**, but that is difficult to translate into a therapy.

The investigators used human induced pluripotent stem cells, which are adult cells that have been taken “back in time” to an early embryonic state, to generate young mononuclear phagocytes. **When the young cells were infused into aging mice or a mouse model of Alzheimer’s disease**, investigators noted several important changes.

First, the mice receiving the young cells performed better on memory tests than mice without cell treatment. These mice were also found to have more “mossy cells” in the hippocampus, a brain region critical for learning and memory.

For those interested, here’s the link to the peer reviewed journal article:

https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202417848

INB4 young people are encouraged to donate blood, so older people can squeeze in maybe three extra years.